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. 2022 Oct 31;17(10):e0277020. doi: 10.1371/journal.pone.0277020

Table 1. Demographic and baseline characteristics.

Variables ENI
(n = 19)
Non ENI
(n = 19)
P Value
Demographics
Age, years, mean ± standard deviation 65.4±9.21 68.4±14.86 0.452
Gender, male, n (%) 7(36.8) 8(42.1) 0.740
Current smoking, n (%) 8(42.1) 11(57.9) 0.330
Alcohol consumption, n (%) 5(26.3) 6(31.6) 0.721
Medical history, n (%)
Stroke 3(15.8) 4(21.1) 0.676
Hypertension 10(52.6) 10(52.6) 1.000
Diabetes mellitus 5(26.3) 5(26.3) 1.000
Atrial fibrillation 4(21.1) 4(21.1) 1.000
Congestive heart failure 3(15.8) 4(21.1) 0.676
Previous use of antiplatelet 2(10.5) 3(15.8) 0.631
Baseline scales, mean ± standard deviation
Systolic blood pressure, mmHg 158.8±24.63 153.0±25.09 0.478
Diastolic blood pressure, mmHg 87.3±9.68 90.0±15.95 0.527
Blood glucose, mmol/L 9.19±4.68 7.68±2.92 0.276
Symptom onset to thrombolysis time, min 160.1±49.11 157.0±53.87 0.854
NIHSS score at admission 9.4±5.69 8.1±5.65 0.462
TOAST classification, n (%) 0.185
Large artery atherosclerosis 11(57.9) 10(52.6)
Small artery occlusion 5(26.3) 4(21.1)
Cardiogenic embolism 1(5.3) 5(26.3)
Undetermined cause 2(10.5) 0(0.0)

ENI, early neurologic improvement; NIHSS, National Institute of Health Stroke Scale; TOAST, the Trial of Org 10172 in Acute Stroke Treatment.