Table 2. Patients’ characteristics.
Characteristics | Dystrophin disruption groups | p value | ||
---|---|---|---|---|
Dp427 (N = 10) | Dp140 (N = 37) | Dp71 (N = 4) | ||
Age | 10.9 ± 2.6 | 11.1 ± 3.1 | 9.5 ± 2.08 | 0.572 |
Disease onset | 6.7 ± 2.9 | 5.8 ± 2.3 | 5.8 ±4.3 | 0.639 |
Ambulatory | 0.349 | |||
Early ambulatory | 4 (36%) | 4 (10.3%) | 0 (0%) | |
Late ambulatory | 0 (0%) | 2 (5.1%) | 1 (25%) | |
Non-ambulatory | 5 (45%) | 24 (61.5%) | 2 (50%) | |
Family history of disease | 2 (20%) | 10 (27%) | 1 (25%) | 0.923 |
Physical Examination | ||||
Pseudohypertrophy | 4 (36%) | 19 (51.4%) | 1 (35%) | 0.420 |
Gower sign | 5 (45%) | 18 (48.6%) | 3 (75%) | 0.759 |
Laboratories result | ||||
CK (U/L) | 4314 (1,077–17,238) | 6,788 (444–16,550) | 6,681 (3,335–7,875) | 0.604 |
CKMB (U/L) | 145 (91–399) | 288 (49–831) | 222 (173–311) | 0.384 |
Positive biopsy | 3 (27%) | 11 (29.7%) | 3 (75%) | 0.365 |
Note: significance set as p<0.05; CK, creatine kinase; CKMB, creatine kinase myocardial band.