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. 2022 Oct 31;17(10):e0276640. doi: 10.1371/journal.pone.0276640

Table 2. Patients’ characteristics.

Characteristics Dystrophin disruption groups p value
Dp427 (N = 10) Dp140 (N = 37) Dp71 (N = 4)
Age 10.9 ± 2.6 11.1 ± 3.1 9.5 ± 2.08 0.572
Disease onset 6.7 ± 2.9 5.8 ± 2.3 5.8 ±4.3 0.639
Ambulatory 0.349
    Early ambulatory 4 (36%) 4 (10.3%) 0 (0%)
    Late ambulatory 0 (0%) 2 (5.1%) 1 (25%)
    Non-ambulatory 5 (45%) 24 (61.5%) 2 (50%)
Family history of disease 2 (20%) 10 (27%) 1 (25%) 0.923
Physical Examination
    Pseudohypertrophy 4 (36%) 19 (51.4%) 1 (35%) 0.420
    Gower sign 5 (45%) 18 (48.6%) 3 (75%) 0.759
Laboratories result
    CK (U/L) 4314 (1,077–17,238) 6,788 (444–16,550) 6,681 (3,335–7,875) 0.604
    CKMB (U/L) 145 (91–399) 288 (49–831) 222 (173–311) 0.384
    Positive biopsy 3 (27%) 11 (29.7%) 3 (75%) 0.365

Note: significance set as p<0.05; CK, creatine kinase; CKMB, creatine kinase myocardial band.