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. 2022 Nov 1;1869(2):166592. doi: 10.1016/j.bbadis.2022.166592

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© 2022 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 3 — Dot plot of routine biochemical indices revealed significant (P-value ≤0.05) differences, describing a general C19 and a severity-based C19 signature when compared to the Ctrl-infl (A) and Ctrl-noninfl group (B) as well as the trajectory (C). Points represent significant level differences in the respective group comparison, where the colour of the dots describes the effect size (log2 fold change) and the size of the dots the significance niveau (adjusted P-value). D: Distribution of selected biochemical indices over the course of the disease.