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. 2022 Nov 1;1869(2):166592. doi: 10.1016/j.bbadis.2022.166592

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© 2022 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 6 — A: COVID-19 phase-dependent differential regulation of plasma proteins and their intersections. B: Differentially regulated plasma proteins and their intersections for disease severity comparisons (C19-ox/C19-nonox) considering different disease phases; purple: inflammation; blue: coagulation; brown: remodeling; green: metabolism C: Intersections of differentially abundant plasma proteins for different disease phases in C19-nonox. D: Log2 fold-change of phase-regulated proteins. Protein symbols in bold are associated with NETosis, IL-1, or TNF signaling. E: Overlapping pathways of all disease phase comparisons.