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. 2022 Oct 3;3(1):421–432. doi: 10.1089/neur.2022.0040

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© Basavaraju G. Sanganahalli et al., 2022; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 3. — Average RSFC obtained using seed voxels from both hemispheres across sham (n = 7) and SCI groups (n = 11). (A–C) S1_FL representation and (D–F) M1 representation. Color bar represents the correlation coefficient (cc). Significant difference map of correlation coefficient values (SCI > sham; color bar representing the difference in cc). Activated voxels were statistically determined using a two-tailed t-test with an activation threshold of p < 0.05 and corrected for multiple comparisons by a family-wise error control using a cluster size of 30 voxels. Average RSFC maps represent 12 seed voxels × 3 experimental runs × 7 animals = 252 for sham and 12 seed voxels × 3 experimental runs × 11 animals = 396 for SCI. Image orientation is in the neurological convention (image left/right is subject left/right). RSFC, resting-state functional connectivity; SCI, spinal cord injury.