Table. Antimicrobial resistance gene profiles in 3 clusters of Vibrio cholerae O139 isolates from Zhejiang Province, China, 1994–2018, and in groups of isolates from outside of China.
| Gene | Cluster or group, no. (%) |
||||
|---|---|---|---|---|---|
| Cluster 1, n = 11 | Cluster 2, n = 63 | Cluster 3, n = 32 | Lineage 1 non-China, n = 15 | Other* non-China, n = 33 | |
| aph (3′′)-Ib | 11 (100) | 59 (93.65) | 31 (96.88) | 6 (40) | 33 (100) |
| aph (6)-Id | 11 (100) | 59 (93.65) | 31 (96.88) | 6 (40) | 33 (100) |
| dfrA18 | 11 (100) | 35 (55.56) | 29 (90.63) | 1 (6.67) | 33 (100) |
| sul2 | 11 (100) | 63 (100) | 32 (100) | 5 (33.33) | 33 (100) |
| varG† | 11 (100) | 63 (100) | 32 (100) | 15 (100) | 33 (100) |
| catB9† | 11 (100) | 63 (100) | 32 (100) | 15 (100) | 33 (100) |
| floR | 11 (100) | 59 (93.65) | 31 (96.88) | 6 (40) | 33 (100) |
| bla TEM-1 | 0 | 61 (96.83) | 0 | 0 | 0 |
| aph(3′)-Ia | 0 | 57 (90.48) | 23 (71.88) | 0 | 0 |
| aadA2 | 0 | 56 (88.89) | 5 (15.63) | 0 | 0 |
| catA2 | 0 | 56 (88.89) | 4 (12.50) | 0 | 0 |
| tet(D) | 0 | 55 (87.30 | 9 (28.13) | 0 | 0 |
| sul1 | 0 | 54 (85.71) | 26 (81.25) | 0 | 0 |
| aac(3)-IId | 0 | 53 (84.13) | 0 | 0 | 0 |
| mph(E) | 0 | 52 (82.54) | 2 (6.25) | 0 | 0 |
| msr(E) | 0 | 52 (82.54) | 2 (6.25) | 0 | 0 |
| mph(A) | 0 | 0 | 22 (68.75) | 0 | 0 |
| tet(M) | 0 | 0 | 21 (65.63) | 0 | 0 |
| dfrA12 | 0 | 2 (3.17) | 21 (65.63) | 0 | 0 |
| tet (Y) | 0 | 5 (7.94) | 2 (6.25) | 0 | 0 |
| aac(6')-Ib-cr5 | 0 | 0 | 1 (3.13) | 0 | 0 |
| aadA16 | 0 | 0 | 4 (12.50) | 0 | 0 |
| aadA3 | 0 | 0 | 4 (12.50) | 0 | 0 |
| arr-3 | 0 | 0 | 4 (12.50) | 0 | 0 |
| bla CMY-2 | 0 | 0 | 1 (3.13) | 0 | 0 |
| bla OXA-1 | 0 | 0 | 1 (3.13) | 0 | 0 |
| catB3 | 0 | 0 | 1 (3.13) | 0 | 0 |
| dfrA27 | 0 | 0 | 4 (12.50) | 0 | 0 |
| dfrA32 | 0 | 0 | 1 (3.13) | 0 | 0 |
| ere(A) | 0 | 0 | 1 (3.13) | 0 | 0 |
| mph(F) | 0 | 0 | 1 (3.13) | 0 | 0 |
| qnrA1 | 0 | 0 | 3 (9.38) | 0 | 0 |
| qnrA7 | 0 | 0 | 1 (3.13) | 0 | 0 |
| tet(A) | 0 | 0 | 4 (12.50) | 0 | 0 |
*Isolates not grouped in lineage 1 and clusters 1–3 and not isolated in China (Appendix 1 Table 4). †Genes that have not been associated with phenotypic resistance, determined on the basis of published data up to now.