Table 3. Studies comparing CDTL and mechanical thrombectomy for Paget Schroetter syndrome.
| Study | Year | Intervention | Clinical outcomes |
|---|---|---|---|
| Schneider et al. (14) | 2003 | AngioJet debulking followed by CDTL | • Average thrombolysis time of 12 hours overall |
| • 60% of patients found to have post-decompression residual stenosis, successfully managed via PTA | |||
| O’Sullivan et al. (21) | 2007 | Trellis catheter followed by surgical decompression | • 50–95% clot removed in 82% of patients |
| • >95% clot removed in 3 patients | |||
| • <50% clot removed in 1 patient | |||
| • Average thrombolysis time of 91 minutes | |||
| Elman et al. (16) | 2006 | Mechanical thrombectomy versus CDTL | • >50% clot removed in 93% of patients receiving mechanical thrombectomy |
| • >50% clot removed in 79% of patients receiving CDTL | |||
| Zurkiya et al. (10) | 2018 | CDTL with or without post surgical decompression balloon angioplasty | • 86% of patients undergoing CDTL had residual SV stenosis managed with balloon angioplasty |
| • 4 patients undergoing CDTL had chronic SV occlusion | |||
| Wooster et al. (8) | 2019 | Endovascular intervention with or without surgical decompression | • 67% of patients underwent endovascular repair including |
| • 23 PTA | |||
| • 13 Stent | |||
| • 18 venous reconstruction | |||
| Bashir et al. | 2022 | CDTL with surgical decompression | • Median thrombolysis time of 22 hours (6–46) |
| • 88% of patients had fully patent SV following decompression | |||
| • 100% of patients asymptomatic at follow-up |
CDTL, catheter-directed thrombolysis; PTA, percutaneous transluminal angioplasty; SV, subclavian vein.