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. 2022 Nov;12(11):5209–5221. doi: 10.21037/qims-21-1208

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2022 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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A 28-year-old man with a 0.7 cm × 0.6 cm solid thyroid nodule in the right lobe of his thyroid was confirmed as papillary carcinoma via postoperative pathological results. ROI was selected in the reference area (yellow lines) and analysis area (green lines). Arrowheads indicate nodule margins. (A) Conventional US image; (B) CEUS image; (C) dynamic perfusion curves; (D) histopathologic image (hematoxylin-eosin staining, ×40). ROI, region of interest; US, ultrasound; CEUS, contrast-enhanced ultrasound.