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Flow chart of the systematic analysis of diagnostic genes and pharmacological treatment of RIAs. GEO, gene expression omnibus; PPI, protein-protein interaction; DEG, differentially expressed gene; WGCNA, weighted gene co-expression network analysis; LASSO, least absolute shrinkage and selection operator; GO, Gene Ontology; KEGG, The Kyoto Encyclopedia of Genes and Genomes; AUC, area under the curve; ROC, receiver operating characteristic; RIAs, ruptured intracranial aneurysms.
