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. 2022 Sep 14;160(1):55–65. doi: 10.1007/s11060-022-04105-5

Table 4.

Univariate analysis demonstrating the association between tumor characteristics and cranial nerve deficits

112 Surgeries in 101 patients: 96 retrosigmoid, 16 subtemporal/pterional Cranial nerve deficits preoperatively vs. at follow-up
Preop. with CN deficits p-value CN status unchanged CN status improved CN status worsening p-value at follow-up
Age
  ≤ 60 years [n = 47] 63.8% .287 46.8% 34% 19.1% .464
  > 60 years [n = 54] 74.1% 38.9% 31.5% 29.6%
Gender
 Male [n = 16] 81.3% .378 56.3% 25.0% 18.8% .483
 Female [n = 85] 67.1% 40.0% 34.1% 25.9%
Two-stage surgery
 No [n = 100] 70% 1.0 43% 32% 25% .293
 Yes [n = 12] 75% 66.7% 16.7% 16.7%
Cavernous sinus infiltration
 No [n = 89] 68.5% .448 46.1% 31.5% 22.5% .711
 Yes [n = 23] 78.3% 43.5% 26.1% 30.4%
Tumor size
  ≤ 10 cm3 [n = 50] 66% .828 44% 34% 22% .769
  > 10 cm3 [n = 46] 69.6% 39.1% 32.6% 28.3%
WHO grade
 WHO grade 1 [n = 99] 69.7% 1.0 47.5% 29.3% 23.2% .336
 WHO grade 2 [n = 12] 75.0% 25% 41.7% 33.3%
Tumor consistency
 Soft [n = 69] 68.1% .528 50.7% 33.3% 15.9% .038
 Firm [n = 43] 74.4% 37.2% 25.6% 37.2%
Tumor surface
 Smooth [n = 77] 70.1% 1.0 48.1% 31.2% 20.8% .466
 Cauliflower [n = 35] 71.4% 40% 28.6% 31.4%
Tumor location
 Unilateral [n = 85] 70.6% 1.0 48.2% 34.1% 17.6% .016
 Bilateral [n = 27] 70.4% 37% 18.5% 44.4%
Tumor vascularity
 Low [n = 81] 69.1% .651 45.7% 28.4% 25.9% .679
 High [n = 31] 74.2% 45.2% 35.5% 19.4%
Proposed grading system
 Type I [n = 59] 67.8% .560 52.5% 35.6% 11.9% .010
 Type II [n = 10] 90.0% 40.0% 50.0% 10.0%
 Type III [n = 27] 70.4% 37.0% 18.5% 44.4%
 Type IV [n = 16] 68.8% 37.5% 18.8% 43.8%
 Type I [n = 59] 67.8% .539 52.5% 35.6% 11.9% .006
 All other types [n = 53] 73.6% 37.7% 24.5% 37.7%