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. 2022 Oct 31;14:51. doi: 10.1038/s41368-022-00199-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — tFNAs-ASOs inhibit the formation of bacterial biofilms. a Schematic representation of the fabrication of tFNAs-ASOs, and the tFNA-ASO-mediated suppression of bacterial biofilm formation via the regulation of biofilm-related genes. b SEM images reveal the architecture of biofilms after treatment with tFNAs, ASOs, and tFNAs-ASOs. c The levels of targeted EPS synthesis-related genes were examined using qPCR. Reproduced with permission.⁵⁷ Copyright ©, 2020 Springer Nature