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. 2022 May 16;43(11):2929–2945. doi: 10.1038/s41401-022-00914-6

Fig. 2. UUO caused gradual increases in metabolites that paralleled progressive TIF.

Fig. 2

a Relative intensities of four significantly altered metabolites in the obstructed kidney tissues of UUO mice at Weeks 1, 2 and 3. b Chemical structures of the four metabolites. c Relative intensities of the four significantly altered metabolites in the serum of UUO mice at Weeks 1, 2 and 3. **P < 0.01 compared with the sham group; ^P < 0.05, ^^P < 0.01 compared with the UUO group at Week 1; #P < 0.05, ##P < 0.01 compared with the UUO group at Week 2.