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. 2022 May 16;43(11):2929–2945. doi: 10.1038/s41401-022-00914-6

Fig. 5. MP is a specific AhR mediator in kidney proximal tubular epithelial cells, macrophages and kidney interstitial fibroblasts.

Fig. 5

a The mRNA expression of AhR in NRK-52E cells transfected with CTL shRNA or AhR shRNA. b The mRNA expression of CYP1A1, CYP1A2, CYP1B1 and COX-2 in MP-induced NRK-52E cells treated with AhR shRNA. c The mRNA expression of AhR in RAW 264.7 cells transfected with CTL shRNA or AhR shRNA. d The mRNA expression of CYP1A1, CYP1A2, CYP1B1 and COX-2 in MP-induced RAW 264.7 cells treated with AhR shRNA. e The mRNA expression of AhR in NRK-49F cells transfected with CTL shRNA or AhR shRNA. f The mRNA expression of CYP1A1, CYP1A2, CYP1B1 and COX-2 in MP-induced NRK-49F cells treated with AhR shRNA. **P < 0.01 vs the CTL, scramble shRNA or scramble group; ##P < 0.01 vs the scramble group treated with MP.