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. 2022 May 16;43(11):2929–2945. doi: 10.1038/s41401-022-00914-6

Fig. 9. MP is a crucial component of the cell–cell and cell-microenvironment interactions in TIF.

Fig. 9

MP activated the AhR signalling pathway in kidney proximal tubular epithelial cells, macrophages and kidney interstitial fibroblasts, as well as in mice. MP mediated renal fibrosis through EMT and MMT by activating the AhR signalling pathway.