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. 2022 Oct 31;13:6522. doi: 10.1038/s41467-022-34340-3

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Fig. 6 — a ftChyD uses NH₄Cl or l-Gln to catalyse the amidation of 10 to form 11. b LC-MS analysis of the incorporation of ¹⁵N into 11. The EICs were extracted at m/z 338 [M + H]⁺ for 10 and ¹⁵N-labelled 11, and m/z 337 [M + H]⁺ for 11. c ftChyE catalyses the hydrolysis of 11 and 10 to form 2 and 3, respectively. d ftChyM is an α-KGD that catalyses the C-N bond oxidative cleavage of 11 to form 4 via a possible intermediate 12. e Conversion of 4 to 6 shows the alkaline-induced spontaneous C-2-N-3 bond closure.