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. 2022 Nov 1;12(10):146. doi: 10.1038/s41408-022-00741-2

Table 7.

Maximum CRS and ICANS in multiple myeloma cohort.

Early G-CSF* (N = 24) Controla (N = 23) Overall (N = 47)
CRS gradeb
0 4 (16.7%) 3 (13.0%) 7 (14.9%)
1 12 (50.0%) 11 (47.8%) 23 (48.9%)
2 8 (33.3%) 8 (34.8%) 16 (34.0%)
3 0 (0%) 1 (4.3%) 1 (2.1%)
ICANS gradeb
0 21 (87.5%) 18 (78.3%) 39 (83.0%)
1 1 (4.2%) 3 (13.0%) 4 (8.5%)
2 1 (4.2%) 0 (0%) 1 (2.1%)
3 0 (0%) 2 (8.7%) 2 (4.3%)
4 1 (4.2%) 0 (0%) 1 (2.1%)

*Early G-CSF group received G-CSF within ≤2 days after CAR T.

aControl group either received G-CSF ≥ 3 days after CAR T (N = 21) or were not exposed to G-CSF (N = 2).

bMaximum CRS/ICANS grade per ASTCT consensus criteria.