Table 7.
Early G-CSF* (N = 24) | Controla (N = 23) | Overall (N = 47) | |
---|---|---|---|
CRS gradeb | |||
0 | 4 (16.7%) | 3 (13.0%) | 7 (14.9%) |
1 | 12 (50.0%) | 11 (47.8%) | 23 (48.9%) |
2 | 8 (33.3%) | 8 (34.8%) | 16 (34.0%) |
3 | 0 (0%) | 1 (4.3%) | 1 (2.1%) |
ICANS gradeb | |||
0 | 21 (87.5%) | 18 (78.3%) | 39 (83.0%) |
1 | 1 (4.2%) | 3 (13.0%) | 4 (8.5%) |
2 | 1 (4.2%) | 0 (0%) | 1 (2.1%) |
3 | 0 (0%) | 2 (8.7%) | 2 (4.3%) |
4 | 1 (4.2%) | 0 (0%) | 1 (2.1%) |
*Early G-CSF group received G-CSF within ≤2 days after CAR T.
aControl group either received G-CSF ≥ 3 days after CAR T (N = 21) or were not exposed to G-CSF (N = 2).
bMaximum CRS/ICANS grade per ASTCT consensus criteria.