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. 2022 Apr 28;43(11):2749–2758. doi: 10.1038/s41401-022-00910-w

Fig. 3. Nucleic acid-loaded NDDSs for anti-PD-1/PD-L1 therapy.

Fig. 3

a Preparation of siRNA and PPa-coloaded micelleplexes. b Mechanism of micelleplex-enhanced antitumor efficacy via RNAi of PD-L1 and PDT. Adapted with permission from [55]. Copyright (2016) American Chemical Society. c Schematic illustration of the ANP/plasmid nanoparticles for photothermal genome editing of PD-L1. Adapted with permission from [88]. Copyright (2021) John Wiley & Sons, Inc.