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. 2022 Oct 31;12(12):333. doi: 10.1007/s13205-022-03401-1

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© King Abdulaziz City for Science and Technology 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 7 — A Fluorescence Microscopy results of yeast Knock-outs expressing FUS and TDP‒43 Wild type and Mutants. All the knock-outs showed a significant reduction in protein aggregates. Imaging was carried out in the dark field (blue light) and white light. Images were arranged using PhotoScape. B Graph representing fluorescence quantification results of yeast Knock-outs expressing FUS and TDP‒43 Wild type and Mutants. The quantification results had a strong correlation with imaging results. Fluorescence quantification was carried out using ImageJ software (⋆ represents P ≤ 0.05)