Table 2. Associations of Persistent High Inflammation with Recurrent Ischemic Stroke Based on Different Status of LDL-C.

	n (%)	Unadjusted model			Adjusted model＊
		HR	95% CI	P	HR	95% CI	P
Non-persistent high LDL-C level1
Non-persistent high inflammation2	112/1498 (7.5)	Ref.			Ref.
Persistent high inflammation2	33/336 (9.8)	1.33	0.90–1.96	0.15	1.20	0.81–1.79	0.35
Persistent high LDL-C level1
Non-persistent high inflammation	221/2898 (7.3)	Ref.			Ref.
Persistent high inflammation	92/874 (10.5)	1.41	1.11–1.80	0.005	1.29	1.01–1.64	0.04

¹Persistent high LDL-C level refers to LDL-C ≥ 55 mg/dL both at baseline and 3-month, all other statuses of LDL-C were defined as non- persistent high LDL-C level. ²Persistent high inflammation was defined as hsCRP level ≥ 2 mg/L both at baseline and 3-month, other status of hsCRP were defined as non-persistent high inflammation.

^＊Adjusted for age, sex, medical history of diabetes mellitus, cardiocerebrovascular diseases, TOAST classification.