Table 3.
Multivariate analysis for predictors of mortality from 2011 to 2017 in the TAVR cohort.
| Predictor | Odds ratio (95% CI) | P-Value |
|---|---|---|
| Gender | <0.001 | |
| Male | 1.00 (reference) | N/A |
| Female | 1.26 (1.18, 1.35) | <0.001 |
| Age group | <0.001 | |
| 18–49 yrs | 1.00 (reference) | N/A |
| 50–59 yrs | 1.90 (0.97, 3.72) | 0.060 |
| 60–69 yrs | 1.27 (0.67, 2.42) | 0.460 |
| 70–79 yrs | 1.34 (0.71, 2.52) | 0.362 |
| 80–89 yrs | 1.51 (0.80, 2.82) | 0.202 |
| 90 yrs or older | 2.11 (1.12, 3.97) | 0.020 |
| Race | <0.001 | |
| White | 1.00 (reference) | N/A |
| Asian or Pacific Islander | 0.94 (0.67, 1.32) | 0.718 |
| Black | 0.59 (0.47, 0.74) | <0.001 |
| Hispanic | 1.32 (1.13, 1.54) | <0.001 |
| Native American | 2.11 (1.25, 3.57) | 0.005 |
| Comorbidities | ||
| Hypertension | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 0.49 (0.46, 0.53) | <0.001 |
| Hyperlipidemia | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 0.48 (0.45, 0.51) | <0.001 |
| Cerebrovascular disease | 0.058 | |
| No | 1.00 (reference) | N/A |
| Yes | 1.13 (1.00, 1.28) | 0.058 |
| Congestive heart failure | 0.025 | |
| No | 1.00 (reference) | N/A |
| Yes | 1.10 (1.01, 1.20) | 0.025 |
| Diabetes mellitus | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 0.72 (0.66, 0.77) | <0.001 |
| Renal failure | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 1.47 (1.37, 1.57) | <0.001 |
| Chronic pulmonary disease | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 1.17 (1.09, 1.26) | <0.001 |
| Peripheral vascular disorders | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 1.30 (1.21, 1.39) | <0.001 |
| Prior CAD/IHD | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 0.81 (0.74, 0.89) | <0.001 |
| Prior PCI | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 0.59 (0.52, 0.67) | <0.001 |
| Prior cardiac surgery | <0.001 | |
| No | 1.00 (reference) | N/A |
| Yes | 0.61 (0.56, 0.67) | <0.001 |
| Deyo-CCI | ||
| 0 | 1.00 (reference) | N/A |
| 1 | 1.09 (0.91, 1.32) | 0.354 |
| 2 or higher | 1.49 (1.28, 1.74) | <0.001 |
AVR, aortic valve replacement; SAVR, surgical aortic valve replacement; TAVR, transcatheter aortic valve replacement; IHD, ischemic heart disease; PCI, percutaneous coronary intervention; NA, no available.