Table 4.

Multivariable analysis for predictors of TAVR mortality from 2011 to 2017 by sex.

	Male		Female
Predictor	Odds ratio (95% CI)	P-Value	Odds ratio (95% CI)	P-Value
Comorbidities
Hypertension		<0.001		<0.001
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	0.53 (0.47, 0.59)	<0.001	0.46 (0.42, 0.52)	<0.001
Hyperlipidemia		<0.001		<0.001
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	0.46 (0.42, 0.51)	<0.001	0.50 (0.45, 0.55)	<0.001
Cerebrovascular disease		<0.001		0.311
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	1.40 (1.18, 1.66)	<0.001	0.91 (0.76, 1.09)	0.311
Congestive heart failure		<0.001		0.651
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	1.25 (1.11, 1.41)	<0.001	0.97 (0.86, 1.10)	0.651
Diabetes mellitus		<0.001		<0.001
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	0.77 (0.69, 0.86)	<0.001	0.66 (0.59, 0.74)	<0.001
Renal failure		<0.001		<0.001
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	1.55 (1.40, 1.71)	<0.001	1.40 (1.27, 1.54)	<0.001
Chronic pulmonary disease		<0.001		0.224
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	1.30 (1.18, 1.44)	<0.001	1.06 (0.96, 1.18)	0.224
Peripheral vascular disorders		<0.001		<0.001
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	1.27 (1.14, 1.40)	<0.001	1.33 (1.20, 1.47)	<0.001
Prior CAD/IHD		0.004		0.001
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	0.81 (0.71, 0.94)	0.004	0.82 (0.73, 0.93)	0.001
Prior sternotomy		<0.001		<0.001
No	1.00 (reference)	N/A	1.00 (reference)	N/A
Yes	0.61 (0.55, 0.69)	<0.001	0.60 (0.52, 0.69)	<0.001
Deyo-CCI		<0.001		0.001
0	1.00 (reference)	N/A	1.00 (reference)	N/A
1	0.97 (0.71, 1.33)	0.852	1.16 (0.92, 1.47)	0.198
2 or higher	1.69 (1.31, 2.17)	<0.001	1.37 (1.13, 1.67)	0.002

Deyo-CCI, Deyo-Charlson Comorbidity Index; IHD, ischemic heart disease; TAVR, transcatheter aortic valve replacement; NA, no available.