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. 2022 Oct 18;12:978069. doi: 10.3389/fonc.2022.978069

Table 2.

Analyses of NSCLC pooled hazard ratios for OS outcomes by subgroup.

Variables Study, N(%) Number of patients(N) Pooled HR (95%CI) p value for interaction
LMs non-LMs LMs non-LMs
Overall 8 (100) 1245 5614 0.78 (0.68,0.90) 0.72 (0.67,0.78) 0.24
Therapy line
First-line 6 (75) 1002 4720 0.79 (0.67,0.92) 0.72 (0.66,0.79) 0.28
Second- or later-line 2 (25) 243 894 0.77 (0.58,1.02) 0.71 (0.60,0.84) 0.63

NSCLC, non–small cell lung cancer; LMs, liver metastases; OS, overall survival; HR, hazard ratio; CI, confidence interval.