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. 2022 Oct 18;13:963508. doi: 10.3389/fneur.2022.963508

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Copyright © 2022 Li, Li, Si, Zhang, Ni, Zhou, Liu, Xia, Zhang, Gu, Huang, Yin, Shao and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CircRNAs affect IS injury by regulating autophagy. Changing the expression of circ_016719, circHECTD1, circSHOC2, and circ_002598 can induce IS injury by upregulating autophagy. However, changing the expression of circAkap7 and circ-FoxO3 can inhibit IS injury by upregulating autophagy.