Table 2.

Molecular action and signaling pathway regulation of alkaloids.

S. No	Alkaloids	Signaling pathway regulation	References
1.	Indole alkaloids	Inhibit JAK/STAT signaling pathway and Akt/NF-кB signaling pathway	(71)
2.	Isoquinoline alkaloids	Inhibit JAK/STAT signaling pathway	(72)
3.	Benzoquinolizidine alkaloids	Inhibit JAK/STAT signaling pathway	(72)
4.	Pyrrolizidine alkaloids	Suppress the p53 signaling pathway	(73)
5.	Phenanthroindolizidine Alkaloids	Inhibition of NF-κB signaling pathway,	(74)
6.	Benzoquinolizidine alkaloids	Dephosphorylation of PI3K and Akt in the PI3K/Akt signaling pathway	(75)