Table 3. Likelihood of Fast-Track Referral Among Patients With Red-Flag Symptoms or Signs (n = 2115).
| Patient group | Fast-track referral, No. (%) | OR (95% CI)a | P value | |
|---|---|---|---|---|
| Unadjusted | Adjustedb | |||
| MHM | ||||
| No | 765 (42.3) | 1 [Reference] | 1 [Reference] | NA |
| Yes | 94 (30.5) | 0.60 (0.46-0.78) | 0.72 (0.55-0.94) | .02 |
| Age group, y | ||||
| <45 | 9 (24.3) | 0.40 (0.19-0.84) | 0.37 (0.17-0.84) | .02 |
| 45-54 | 62 (46.6) | 1.08 (0.70-1.65) | 1.13 (0.72-1.78) | .59 |
| 55-64 | 134 (44.8) | 1 [Reference] | 1 [Reference] | NA |
| 65-74 | 217 (41.7) | 0.88 (0.65-1.19) | 1.10 (0.80-1.51) | .55 |
| 75-84 | 333 (42.2) | 0.90 (0.67-1.21) | 1.28 (0.95-1.74) | .11 |
| ≥85 | 104 (31.0) | 0.55 (0.38-0.79) | 0.83 (0.57-1.21) | .32 |
| Sex | ||||
| Men | 444 (41.8) | 1 [Reference] | 1 [Reference] | NA |
| Women | 415 (39.4) | 1.08 (0.70-1.65) | 1.13 (0.72-1.78) | .91 |
| Socioeconomic deprivation quintile | ||||
| 1 (least deprived) | 233 (42.4) | 1 [Reference] | 1 [Reference] | NA |
| 2 | 196 (40.6) | 0.93 (0.72-1.19) | 0.88 (0.68-1.15) | .36 |
| 3 | 218 (47.1) | 1.21 (0.95-1.55) | 1.18 (0.92-1.51) | .20 |
| 4 | 132 (36.1) | 0.77 (0.59-1.00) | 0.76 (0.58-1.00) | .05 |
| 5 (most deprived) | 80 (31.6) | 0.63 (0.45-0.88) | 0.67 (0.48-0.95) | .02 |
| CCI score | ||||
| 0 | 529 (45.8) | 1 [Reference] | 1 [Reference] | NA |
| 1 | 188 (40.0) | 0.79 (0.65-0.96) | 0.92 (0.74-1.14) | .43 |
| 2 | 85 (34.4) | 0.62 (0.46-0.84) | 0.76 (0.56-1.04) | .09 |
| ≥3 | 57 (23.5) | 0.36 (0.26-0.51) | 0.46 (0.32-0.65) | <.001 |
| IBS or DD | ||||
| No | 807 (41.9) | 1 [Reference] | 1 [Reference] | NA |
| Yes | 52 (27.5) | 0.53 (0.37-0.74) | 0.54 (0.38-0.77) | .001 |
| Visits to GP in 1-12 mo before cancer diagnosis, No. | ||||
| 0 | 9 (33.3) | 0.88 (0.39-1.97) | 0.96 (0.43-2.14) | .92 |
| 1-4 | 103 (57.5) | 2.38 (1.72-3.31) | 1.90 (1.35-2.67) | <.001 |
| 5-9 | 188 (51.2) | 1.85 (1.48-2.31) | 1.54 (1.21-1.94) | <.001 |
| ≥10 | 559 (36.3) | 1 [Reference] | 1 [Reference] | NA |
| Type of symptom in 24 mo before cancer diagnosis | ||||
| Rectal bleeding or CIBH | 387 (45.0) | 1 [Reference] | 1 [Reference] | NA |
| Anemia (only red flag) | 472 (37.6) | 0.74 (0.61-0.89) | 0.80 (0.65-0.97) | .02 |
Abbreviations: CCI, Charlson Comorbidity Index; CIBH, change in bowel habit; DD, diverticular disease; IBS, irritable bowel syndrome; MHM, mental health morbidity; NA, not applicable; OR, odds ratio.
a
Logistic regression ORs and 95% CIs are presented.
b
The adjusted model includes all variables listed in the table.