Table 2. IC50 Values for the Cell Lines Incubated with the Samples for 72 ha.
IC50(μg mL–1) |
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MCF-7 |
PANC-1 |
HepG2 |
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sample | NPb(μg mL–1) | equivc FUDR (μg mL–1) | equiv CARB (μg mL–1) | NP (μg mL–1) | equiv FUDR (μg mL–1) | equiv CARB (μg mL–1) | NP (μg mL–1) | equiv FUDR (μg mL–1) | equiv CARB (μg mL–1) |
MOF-808 | - | - | - | - | - | - | - | - | - |
FUDR@MOF-808 | - | - | - | - | - | - | - | - | - |
CARB@MOF-808 | - | - | - | 96.7 | - | 10.6 | - | - | - |
(FUDR+CARB)@MOF-808 | 45.9 | 0.27 | 4.2 | 17.8 | 0.11 | 1.6 | 42.3 | 0.25 | 3.9 |
PAAMAM@MOF-808 | - | - | - | - | - | - | - | - | - |
PAAMAM@(FUDR+CARB)@MOF-808 | 100 | 0.46 | 8.3 | 82.6 | 0.38 | 6.8 | 28.7 | 0.13 | 2.4 |
MOF-808_act | - | - | - | - | - | - | - | - | - |
FUDR@MOF-808_act | - | - | - | - | - | - | - | - | - |
CARB@MOF-808_act | 39.4 | - | 5.4 | 8.4 | - | 1.2 | 24.0 | - | 3.3 |
(FUDR+CARB)@MOF-808_act | 36.4 | 0.23 | 4.4 | 10.2 | 0.06 | 1.2 | 18.0 | 0.11 | 2.2 |
PAAMAM@MOF-808_act | - | - | - | - | - | - | - | - | - |
PAAMAM@(FUDR+CARB)@MOF-808_act | - | - | - | 94 | 0.65 | 9.0 | 18.5 | 0.13 | 1.8 |
FUDR | - | - | - | - | 20.0 | - | - | 14.0 | - |
CARB | - | - | 59.4 | - | - | - | - | 15.8 | |
PAAMAM | - | - | - | - | - | - | - | - | - |
Unreported values are the values that could not be determined in the used sample concentration range.
NP: nanoparticle;
equiv: equivalent.