Fig. 8.

The population ensemble of β-barrel oligomers. a) The average probability of β-barrel formation formed by each type of amylin peptide is calculated using all the 1000 ns simulation trajectories for each type of peptide. b) Representative β-barrel structure formed by hIAPP and hIAPP(S20G) peptide. Three representative β-barrel structures formed by each type of amylin peptide are presented in two different views (side and top). Due to the β-barrel being extremely heterogeneous in structures, three representative β-barrels are randomly selected from the top-three most populated β-barrel trajectories.