Manhattan plot from the meta-analysis of male fertility and reproduction traits [percent of sperm anomalies–head, percent of sperm anomalies–tail, percent of motile sperm, concentration (million sperm/mL), ejaculate volume, and insemination success (sire nonreturn rate)]. The analysis considered 11,804,781 genome-wide variants, with the green line representing a significance threshold of P < 4.24 × 10−9.