Table 2.

Effects of experimental treatments on diarrhea prevalence and days treated with antibiotics in Holstein calves

Item	Treatment1				SEM	P-value
	OD	OW	TD	TW
Onset of diarrhea, d	7.58	7.91	7.31	7.71	0.49	0.86
Duration of diarrhea, d	5.00	4.83	4.80	4.00	0.38	0.61
Days treated with antibiotics2	5.17	5.09	6.10	5.10	0.36	0.39

¹Treatments were a combination of 2 milk and milk replacer feeding frequencies (once versus twice daily) and 2 starter DM levels (91.1 and 50% DM), and included (1) once daily + dry starter diet (OD), (2) once daily + wet starter diet (OW), (3) twice daily + dry starter diet (TD), and (4) twice daily + wet starter diet (TW).

²The following antibiotics were used in accordance with the established veterinarian protocol: sodium sulfadiazine + trimethoprim (Trisul tablet, Zagros Pharmed Pars Co.), enrofloxacin (Enrocin, Razak Laboratories Co.), 1% neomycin (ScourSTOP, Livestock Drugs Production Co.), 20% apramycin (Apramax, Rooyan Darou Co.), and florfenicol (Razak Laboratories Co.).