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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Neurotoxicol Teratol. 2022 Mar 24;91:107090. doi: 10.1016/j.ntt.2022.107090

Table 4.

Positive acute toxicology results and self-reported use endorsements for participants with confirmed positive hair results, by drug class.

Cocaine Opiates Amphetamines THCCOOH Natural cannabinoids Alcohol Nicotine
(n = 13) (n = 2) (n = 59) (n = 25) (n = 22) (n = 9) (n = 19)
Self-reported use:
 Alcohol sips 38.5% 50% 40.7% 48.0% 59.1% 66.7% 52.6%
 Alcohol full drink 0% 0% 0 4.0% 4.5% 0% 0%
 Nicotine puffs 15.4% 50% 5.1% 16.0% 22.7% 11.1% 21.1%
 Nicotine more than puff 7.7% 0% 0% 4.0% 4.5% 11.1% 5.3%
 Cannabis puff 7.7% 50% 0% 12.0% 9.1% 11.1% 10.5%
 Cannabis more than puff 7.7% 50% 0% 4.0% 4.5% 11.1% 5.3%
 Other drugs 0% 0% 2% 0% 0% 0% 5%
Hair analyte confirmationb
 Cocained 13/13
 Benzoylecgonine 12/12
 Norcocaine 2/11
 Oxymorphonec 2/2
 Amphetaminese 52/59
 Methamphetamine 9/51
 THCCOOH 25/25 10/11
 THC 9/10 21/22
 CBN 3/5 5/7
 CBD 5/5 8/11
 THCV 0/2 0/4
 ETG 9/9
 Cotinine 18/19
 3-Hydroxycotinne 6/11
 Norcotinine 1/1
 Nornicotine 8/8
Draeger oral fluid testf
 Amphetamine 1/1a 0/0 30/30a 0/3 2/3a 0/0 2/4a
NicAlertg 0/4 0/0 0/2 1/3 1/3 0/0 1/1

Notes: 11-nor-9-carboxy-tetrahydrocannabinol = THCCOOH, Δ9-tetrahydrocannabinol = THC, cannabidiol = CBD, cannabinol = CBN, Δ9-tetrahydrocannabivarin = THCV; ETG = ethyl glucuronide

a

Positive results are consistent with the youth’s prescription medication.

b

Variation in analyte n due to insufficient quantity of hair (e.g., norcocaine; THCV).

c

Other opioids tested for (fentanyl, codeine, morphine, 6-acetylmorphine, hydrocodone, hydromorphone, and oxycodone) were negative for all.

d

Other cocaine metabolites tested for (cocaethylene, metahydroxycocaine, orthohydroxycocaine, and parahydroxycocaine) were all negative.

e

Other amphetamines tested for (MDA, MDEA, and MDMA) were all negative.

f

Seven drug classes (cocaine, opiates, cannabis, benzodiazepines, amphetamine, methamphetamine, and methadone) were tested as described in the primary manuscript. Only drug classes with a positive are displayed here.

g

NicAlert is a urinary cotinine screen. Positive results on NicAlert here indicate urinary cotinine results at a level which indicates recent, personal nicotine exposure.