Table 3.

Predictors of all-cause mortality or HF Hospitalization

	Hazard ratio (95% CI)	p
A. Univariable Cox Models for All-Cause Mortality or HF Hospitalization
Clinical History
Age (per 10 years)	1.53 (1.02–2.29)	0.04
Male gender	0.73 (0.29–1.84)	0.50
Hypertension	2.25 (0.67–7.54)	0.19
Diabetes mellitus	1.55 (0.69–3.46)	0.29
Family history CAD	0.91 (0.36–2.29)	0.83
Tobacco use	0.67 (0.30–1.48)	0.32
Imaging Markers
*Echocardiography*
Right Ventricle
Ejection fraction (per 10%)	0.62 (0.43–0.89)	0.01
S' (cm/s)	0.97 (0.84–1.12)	0.69
TAPSE (cm)	0.57 (0.20–1.65)	0.30
Left Ventricle
Ejection fraction (per 10%)	0.76 (0.57–1.02)	0.07
Abnormal Peak Longitudinal Strain*
RV global (%)	4.06 (1.47–11.22)	0.007
RV free wall (%)	2.36 (1.01–5.52)	0.048
RV septal (%)	0.85 (0.35–2.10)	0.73
*CMR*
Right Ventricle
Ejection fraction (per 10%)	0.71 (0.51–0.99)	0.04
Left Ventricle
Ejection fraction (per 10%)	0.79 (0.60–1.03)	0.08
Abnormal Peak Longitudinal Strain*
RV global (%)	4.73 (1.60–14.01)	0.005
RV free wall (%)	2.36 (1.01–5.52)	0.048
RV septal (%)	3.36 (0.78–14.47)	0.10
B. Multivariate Cox Models for All-Cause Mortality or HF Hospitalization
Model 1		χ² = 13.34, p = 0.001
Age (per 10 years)	1.60 (1.06–2.41)	0.03
Abnormal RV GLS on STE (%)†	4.51 (1.62–12.58)	0.004
Model 2		χ² = 14.43, p < 0.001
Age (per 10 years)	1.60 (1.06–2.41)	0.03
Abnormal RV GLS on CMR (%)†	5.34 (1.79–15.93)	0.003

Bold values identify a significance of p < 0.05

^*Peak longitudinal strain < 10%

^†RV GLS < 10%