TABLE 1.
Diagnostic accuracies of IgE anti-latex assays at cutoffs yielding maximum diagnostic efficiency
| Parameter | Diagnostic accuracya
|
||
|---|---|---|---|
| ALA (<0.35 kU/literb) | CAP (<0.35 kUA/liter) | HY-TEC (0.11 kU/liter) | |
| Sensitivity | 73.3 (65.7–80.9) | 76.3 (69.1–83.6) | 83.2∗∗ (76.8–89.6)c |
| Specificity | 97.2 (94.8–99.6) | 96.7 (94.0–99.3) | 92.8∗ (89.0–96.6) |
| Positive predictive value | 95.1 (90.8–99.3) | 94.3 (89.9–98.7) | 89.3 (83.9–94.8) |
| Negative predictive value | 83.3 (78.3–88.4) | 84.9 (80.0–89.8) | 88.4∗ (83.8–92.9) |
| Efficiency | 87.1 (83.4–90.9) | 88.1 (84.5–91.7) | 88.7 (85.2–92.3) |
a
Percent; the numbers in parentheses are the 95% confidence interval (n = 311).
b
Cutoff value yielding maximal diagnostic efficiency.
c
Performance parameters of HY-TEC assay based on PST are significantly different from those displayed by the CAP and AlaSTAT systems. ∗, P < 0.05; ∗∗, P < 0.001.