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. 2022 Nov 1;241:109678. doi: 10.1016/j.drugalcdep.2022.109678

Table 2.

Fixed and random parameter estimates for the logistic mixed model predicting the likelihood of MOUD and therapy/counseling receipt between cohorts and over time.


Therapy/Counseling
Buprenorphine
Methadone
Naltrexone

In person
Telehealth
Total
Fixed Effects Est. (SE) adjOR (95% CI) Est. (SE) adjOR (95% CI) Est. (SE) adjOR (95% CI) Est. (SE) adjOR (95% CI) Est. (SE) adjOR (95% CI) Est. (SE) adjOR (95% CI)
Intercept 1.96(0.02)* ** 7.07
(6.80, 7.36)
-3.07(0.03)* ** 0.05
(.04,0.05)
2.07(0.02)* ** 7.96
(7.64, 8.31)
-9.24(0.06) * ** 0.00
(.00,0.00)
-11.26(0.12)* ** 0.00
(.00,0.00)
-9.38(0.08)* ** 0.00
(.00,0.00)
Agea -.18(0.01)* ** 0.83
(.82,0.85)
-0.18(0.01)* ** 0.83
(.81,0.84)
-0.20(0.01)* ** 0.82
(.80,0.83)
-0.48(0.03)* ** 0.62
(.59,0.66)
0.15(0.07)* 1.16
(1.02, 1.32)
-0.41(0.04)* ** 0.67
(.62,0.72)
Gender
(male ref.)
0.30(0.03)* ** 1.34
(1.26, 1.44)
0.32(0.03)* ** 1.38
(1.30, 1.47)
0.37(0.036)* ** 1.45
(1.35, 1.55)
-0.13(0.10) 0.87
(.71, 1.07)
-0.35(0.29) 0.70
(.40, 1.25)
-0.21(0.14) 0.81
(.62, 1.06)
Race/Ethnicity
(White ref.)
0.25(0.02)* ** 1.28
(1.24, 1.33)
0.08(0.02)* ** 1.09
(1.05, 1.13)
0.25(0.02)* ** 1.28
(1.24, 1.33)
-0.47(0.06)* ** 0.62
(.55,0.71)
0.02(0.13) 1.02
(.79, 1.31)
0.19(0.08)* 1.21
(1.04, 1.42)
Rural vs. Urban
(urban ref.)
-0.36(0.02)* ** 0.70
(.67,0.72)
0.04(0.02)* 1.05
(1.01, 1.08)
-0.36(0.02)* ** 0.70
(.67,0.73)
-0.08(0.06)* ** 0.92
(.82, 1.04)
-0.48(0.15)* * 0.62
(.46,0.83)
-0.26(0.09)* * 0.77
(.65,0.91)
CCIa -.15(0.01)* ** 0.86
(.85,0.88)
-0.10(0.01)* ** 0.90
(.89,0.92)
-0.19(0.01)* ** 0.83
(.82,0.85)
-0.10(0.03)* * 0.90
(.85,0.97)
0.09(0.06) 1.09
(.97, 1.22)
-0.17(0.05)* ** 0.84
(.77,0.92)
PDGa .46(0.01)* ** 1.58
(1.55, 1.61)
0.36(0.01)* ** 1.44
(1.42, 1.46)
0.49(0.01)* ** 1.63
(1.60, 1.66)
-0.00(0.03) 1.00
(.95, 1.05)
-0.21(0.07)* * 0.81
(.71,0.93)
0.52(0.03)* ** 1.68
(1.58, 1.80)
Year 2 vs. 1
(year 1 ref.)
-0.93(0.02)* ** 0.40
(.38,0.41)
-0.18(0.02)* ** 0.83
(.79,0.87)
-0.95(0.02)* ** 0.39
(.37,0.40)
-0.57(0.05)* ** 0.57
(.52,0.62)
-5.29(0.18)* ** 0.01
(.00,0.01)
-1.93(0.07)* ** 0.15
(.13,0.17)
Cohort
(comparison cohort ref.)
0.18(0.02)* ** 1.20
(1.15, 1.25)
0.22(0.02)* ** 1.25
(1.19, 1.31)
0.22(0.02)* ** 1.24
(1.19, 1.30)
0.57(0.06)* ** 1.78
(1.59, 1.99)
-0.22(0.12) .80
(.63, 1.01)
0.25(0.07)* ** 1.28
(1.11, 1.48)
Cohort X Year -1.30(0.02)* ** 0.27
(.26,0.29)
2.25(0.03)* ** 9.53
(8.95, 10.20)
-0.81(0.03)* ** 0.45
(.42,0.47)
-0.65(0.06)* ** 0.52
(.46,0.59)
-1.20(0.20)* ** 0.30
(.20,0.45)
-0.55(0.10)* ** 0.58
(.48,0.70)
Random effects SD SD SD SD SD SD
Level 2
Interceptb 1.70 1.28 1.80 15.92 23.00 11.49

Note: CCI = Charlson Comorbidity Index; PDG = Psychiatric Diagnosis Groups; Est. = Estimate; SE = Standard Error; adjOR = Adjusted Odds Ratio; 95% CI = 95% Confidence Interval; SD = Standard Deviation

a Centered and standardized to overcome scale differences and facilitate model convergence

b Parameter estimate of between person variance around fixed intercept.

p < .10, *p < .05, * *p < .01, * **p < .001