Change from baseline in log10viral load estimated from quantitative RT-PCR (mITT population). Shown are mean with SD (bars). Viral load values (log10 copies/mL) were calculated across the S, N and ORF-1ab genes. The number of evaluable patients at each timepoint is shown in Supplementary Data Table S7. mITT, modified intention-to-treat; ASAQ, artesunate-amodiaquine; PA, pyronaridine-artesunate; FPV + NTZ, favipiravir plus nitazoxanide; SOF-DCV, sofosbuvir-daclatasvir.