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Crohn’s disease is a major determinant of oral microbiome structure. [a] Unsupervised principal coordinate analysis [PCoA] conducted on Bray–Curtis dissimilarity matrices demonstrating distinct oral microbiome profiles between subjects with and without CD. [b] PCoA2 score is significantly [p < 0.05] different between subjects with and without CD. [c] PERMANOVA analysis showing four key variables [**p < 0.1, ***p < 0.05] explaining overall oral microbiome community variance.
