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. 2022 Oct 20;18(10):e1009880. doi: 10.1371/journal.pcbi.1009880

Table 1. DeepMR estimates causal effects (CE) accurately with high coverage.

Accuracy is R2. Local corresponds to CEs for individual regions, global for the meta-analysis mean. For global CE accuracy and coverage the first value comes from using MR-Egger and the second from the baseline MR procedure.

Global CE Accuracy Global CE Coverage Local CE CI Coverage
Unconfounded 0.97/0.98 1.00/1.00 0.87
Random 0.98/0.97 1.00/0.96 0.81
Sequence 0.97/0.98 0.98/0.86 0.87
Both 0.78/0.96 0.98/0.92 0.81