Table 4. Clinical features by Ridley Jopling Classification of patients at baseline. Frequency (% of column) n = 157.
TT | BT | BB | BL | LL | Total | |
---|---|---|---|---|---|---|
Total cases | 12 (7.64) | 71 (45.22) | 1 (0.64) | 20 (12.74) | 53 (33.76) | 157 |
Number of skin lesions* | ||||||
0—Pure neural leprosy | 4 (33.3) | 5 (7.1) | 0 (0) | 1 (5.6) | 1 (2.0) | 11 (7.3) |
1 | 7 (58.3) | 14 (20.0) | 0 (0) | 1 (5.6) | 2 (4.1) | 24 (16.0) |
2–10 | 1 (8.3) | 28 (40.0) | 1 (100) | 2 (11.2) | 11 (22.4) | 43 (28.7) |
11–30 | 0 (0) | 17 (24.3) | 0 (0) | 7 (38.9) | 14 (28.6) | 38 (25.3) |
31–100 | 0 (0) | 5 (7.1) | 0 (0) | 4 (22.2) | 18 (36.7) | 27 (18.0) |
>100 | 0 (0) | 1 (1.4) | 0 (0) | 3 (16.7) | 3 (6.1) | 7 (4.6) |
Any Sensory Impairment^ | 5 (41.7) | 34 (48.6) | 1 (100) | 6 (31.6) | 29 (55.8) | 75 (48.7) |
Number of nerves with sensory impairment^ | ||||||
Mean | 0.75 | 1.3 | 4 | 0.84 | 1.77 | 1.34 |
1–2 | 5 (41.7) | 20 (28.6) | 0 | 5 (26.3) | 12 (40.2) | 42 (27.2) |
3–4 | 0 | 10 (14.3) | 1 (100) | 2 (10.5) | 11 (21.1) | 24 (15.6) |
5–6 | 0 | 4 (5.7) | 0 | 0 | 6 (11.5) | 10 (0.06) |
Any Motor Impairment ** | 4 (33.3) | 27 (38.60) | 1 (100) | 7 (35.0) | 21 (41.2) | 60 (39.2) |
Mean bacterial index*** | 0 | 0.45 | 0 | 3.07 | 4.10 | |
Enlarged Nerves § | 6 (50.0) | 37 (52.3) | 1 (100) | 13 (68.4) | 31 (63.3) | 88 (58.3) |
Tender Nerves §§ | 0 | 18 (25.7) | 1 (100) | 2 (11.1) | 9 (18.0) | 32 (21.6) |
Type 1 reaction | 1 (8.3) | 28 (39.4) | 1(100) | 10 (50) | 16 (30.2) | 56 (35.7) |
Erythema nodosum leprosum | 0 | 0 | 1(100) | 4 (20) | 7(13.2) | 12 (7.6) |
Antimicrobial Treatment | ||||||
WHO Paucibacillary MDT | 9 (75) | 48 (68.6) | 0 | 0 | 0 | 57 (36.3) |
WHO Multibacillary MDT | 1 (0.83) | 20 (28.2) | 1 (100.0) | 18 (90.0) | 44 (83.0) | 84 (53.5) |
Monthly ROM§§§ | 1 (0.83) | 1 (0.7) | 0 | 1 (5.0) | 8 (15.1) | 11 (7.0) |
Other | 1 (0.83) | 2 (1.4) | 0 | 1 (5.0) | 1 (0.19) | 5 (3.2) |
TT = tuberculoid leprosy, BT = borderline tuberculoid leprosy, BB = borderline borderline leprosy, BL = borderline lepromatous leprosy, LL = lepromatous leprosy
*7 patients did not have number of lesions recorded, ^complete data for 154 patients, **complete data for 153 patients, ***of 117 patients who had a slit skin smear, §complete data for 151 patients
§§complete data for 148 patients, §§§ rifampicin, ofloxacin and minocycline