Table 3.

Univariable Cox models using baseline parameters as the covariate (n = 25)

Covariates	Univariable
	HR	95% CI	P value
Age, yr	1.003	0.933–1.077	0.944
Sex (female vs male)	4.964	1.357–18.155	0.015
BMI, kg/m2	1.042	0.908–1.197	0.556
ECOG (1/2 vs 0)	2.975	0.820–10.790	0.097
Etiology (other vs alcohol)	1.133	0.390–3.294	0.818
Pretreatment (surgery vs none)	1.281	0.394–4.168	0.681
BCLC stage (A vs B)	0.778	0.100–6.069	0.811
Number of nodules (≥3 vs 2)	1.203	0.255–5.677	0.815
Largest nodule, cma	1.046	0.822–1.332	0.713
13C-MBT, μg/kg/hr	0.993	0.988–0.998	0.010
13C-MBT grade
140–315 μg/kg/hr (2) vs > 315 μg/kg/hr (1)	1.183	0.311–4.506	0.805
< 140 μg/kg/hr (3) vs > 315 μg/kg/hr (1)	13.017	2.385–71.041	0.003
< 140 μg/kg/hr (3) vs 140–315 μg/kg/hr (2)	5.942	1.283–27.521	0.023
ALBI score	9.059	2.944–27.876	<0.001
ALBI grade
2 vs 1	2.025	0.430–9.541	0.372
3 vs 1	16.501	2.200–123.777	0.006
3 vs 2	6.977	1.535–31.722	0.012
Child-Pugh score	1.686	1.181–2.407	0.004
Child-Pugh stage
B vs A	3.175	0.913–11.043	0.069
MELD	1.073	0.931–1.236	0.334

P values < 0.05 are marked in bold.

¹³C-MBT, ¹³C-methacetin breath test; ALBI, albumin-bilirubin; BCLC, Barcelona Clinic Liver Cancer; BMI, body mass index; CI, confidence interval; ECOG, Eastern Cooperative Oncology Group; HR, hazard ratio; MELD, Model for End-Stage Liver Disease.

^aValues of 2 patients missing.