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. 2022 Sep 6;13(10):e00529. doi: 10.14309/ctg.0000000000000529

Table 5.

Extended Cox proportional hazards models (n = 20)

Covariates Univariable
HR 95% CI P value
13C-MBT, μg/kg/hr 0.993 0.987–0.999 0.016
13C-MBT, μg/kg/hr (standardized) 0.297 0.111–0.796 0.016
13C-MBT grade
 140–315 μg/kg/hr (2) vs > 315 μg/kg/hr (1) 1.105 0.222–5.498 0.903
 < 140 μg/kg/hr (3) vs > 315 μg/kg/hr (1) 8.629 1.783–41.769 0.007
 < 140 μg/kg/hr (3) vs 140–315 μg/kg/hr (2) 7.807 1.646–37.033 0.010
ALBI scorea 6.421 2.205–18.696 0.001
ALBI score (standardized)a 4.051 1.813–9.052 0.001
ALBI gradea
 2 vs 1 1.100 0.122–9.968 0.932
 3 vs 1 18.362 1.482–227.505 0.023
 3 vs 2 16.688 2.859–97.428 0.002
Child-Pugh scorea 1.641 1.211–2.223 0.001
Child-Pugh (standardized)a 2.616 1.450–4.719 0.001
Child-Pugh stagea
 B vs A 11.317 0.732–174.987 0.082
 C vs A 14.444 2.373–87.907 0.004
 C vs B 1.276 0.103–15.827 0.849
MELD 1.282 1.077–1.526 0.005
MELD (standardized) 2.781 1.356–5.703 0.005

P values < 0.05 are marked in bold.

13C-MBT, 13C-methacetin breath test; ALBI, albumin-bilirubin; CI, confidence interval; HR, hazard ratio; MELD, Model for End-Stage Liver Disease.

a

Values of 2 patients missing.