TABLE 5.
Diagnostic value for positive blood cultures of clinical and inflammatory variables
| Parameter | Clinical variables
|
Inflammatory mediators
|
||||
|---|---|---|---|---|---|---|
| Clinical infection | Peak temp | Peak WBC count | Peak C3a | Peak IL-6 | Peak sPLA2 | |
| Optimum cutoff value | 39.7 | 16.4 × 109/liter | 14 nmol/liter | 54 pg/ml | 368 ng/ml | |
| Sensitivity (%) | 22 | 48 | 45 | 57 | 64 | 55 |
| Specificity (%) | 92 | 83 | 78 | 75 | 71 | 74 |
| Positive predictive value (%) | 87 | 37 | 31 | 33 | 32 | 30 |
| Negative predictive value (%) | 67 | 88 | 87 | 89 | 90 | 88 |
| Likelihood ratio | 2.75 | 2.79 | 2.12 | 2.26 | 2.20 | 2.05 |