TABLE 2.
Density of uPAR expression on CD14+ monocytes from patients with SPMS, and RRMS and control volunteers
| Group (no. of subjects) | % uPAR+ cells | Mean ± SD MLFI for uPAR+ cellsb |
|---|---|---|
| SPMS (10) | 93 ± 12c | 710 ± 60c |
| RRMS (20) | 45 ± 20c | 421 ± 142c |
| Controls (15) | 18 ± 2 | 110 ± 14 |
| Neurological control (5) | 16 ± 3 | 128 ± 16 |
| Controls treated with LPS (4) | 68 ± 11c | 594 ± 72c |
a
Percent positively stained cells were determined by flow cytometry. CD14+ cells were gated, and their numbers were calculated following subtraction of cells counted with nonspecific isotype control antibody.
b
The MLFI was determined by flow cytometry.
c
Significantly different (P < 0.01) from values for healthy controls or untreated monocytes.