Table 3. Factors predicting recurrence of post-prostatectomy vesicourethral anastomotic stenosis.
Univariate model | Multivariate model | |||||||
---|---|---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | |||
Lower | Upper | Lower | Upper | |||||
Patient’s age | 1.095 | 0.986 | 1.218 | 0.090 | ||||
BMI | 1.061 | 0.932 | 1.208 | 0.373 | ||||
Preoperative PSA level | 1.027 | 0.905 | 1.164 | 0.683 | ||||
Biopsy Gleason grade | 1.418 | 0.881 | 2.283 | 0.150 | ||||
Preoperative clinical T stage | 1.517 | 0.909 | 2.531 | 0.110 | ||||
Post-prostatectomy Gleason grade | 1.020 | 0.671 | 1.552 | 0.924 | ||||
Post-prostatectomy pathological T stage | 1.128 | 0.819 | 1.555 | 0.459 | ||||
Surgical margin positivity | 1.515 | 0.368 | 6.250 | 0.565 | ||||
Post-prostatectomy PSA recurrence | 1.727 | 0.619 | 4.807 | 0.296 | ||||
Pre-prostatectomy ASA score | 1.044 | 0.544 | 2.004 | 0.894 | ||||
Pre-prostatectomy ACCI score | 1.225 | 0.923 | 1.626 | 0.160 | ||||
Presence of preoperative hypertension | 1.440 | 0.570 | 3.636 | 0.440 | ||||
Presence of preoperative diabetes mellitus | 1.387 | 0.547 | 3.512 | 0.491 | ||||
Presence of smoking | 1.763 | 0.841 | 5.448 | 0.266 | ||||
Qmax prior to operation for VUAS (ml/s) | 1.164 | 0.820 | 1.652 | 0.395 | ||||
Postvoid residual volume prior to operation for VUAS (ml) | 1.004 | 0.958 | 1.052 | 0.850 | ||||
Operation type for VUAS | 1.154 | 0.460 | 2.896 | 0.761 | ||||
Time until the occurrence of VUAS (months) | 1.865 | 1.420 | 2.457 | < 0.001* | 1.628 | 1.137 | 2.331 | 0.008* |
VSS score | 5.380 | 2.641 | 10.958 | < 0.001* | 5.380 | 2.641 | 10.958 | < 0.001* |
OR = hazard ratio; CI = confidence interval; BMI = body mass index; PSA = prostate-specific antigen; ASA = American Society of Anesthesiologists; ACCI = age-adjusted Charlson comorbidity index; VUAS = vesicourethral anastomotic stenosis; VSS = Vancouver scar scale; Qmax: peak flow rate.
*P < 0.05; Asterisk (*) indicates statistical significance.