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. Author manuscript; available in PMC: 2023 Jan 6.
Published in final edited form as: Eur Respir J. 2022 Jan 6;59(1):2004532. doi: 10.1183/13993003.04532-2020

FIGURE 4.

FIGURE 4

Baseline levels of lipids associated with tuberculosis (TB) treatment failure in subset analysis. Barplots showing average baseline levels of mean and standard error of residuals for individual lipids that are significantly a) higher or b) lower in treatment failure compared to controls in subset analysis. The subset analysis was limited to those with culture or Xpert-confirmed pulmonary TB diagnosis at baseline as well as culture-confirmed outcomes (failure or cure). The x-axis shows the mean residuals after adjusting for body mass index, age, study site, sex, diabetes, alcohol, smoking and HIV status. Differences are considered significant if their false discovery rate-adjusted p-values <0.05. c) Circular plots showing the individual lipids and the lipid families that are increased or decreased at baseline among failures compared to controls. TG: triacylglycerol; SM: sphingomyelin; LPE: lyso-phosphatidylethanolamine; LPC: lyso-phosphatidylcholine; DG: diacylglycerol; Cer: ceramide; DiHODE: dihydroxyoctadecadienoic acid; CE: cholesterol ester; Oxy: oxylipin.