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. 2022 Sep 27;122(11):1932–1942. doi: 10.1055/a-1914-2094

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 1 — Estimated marginal means of: ( A ) Aβ1–40 across BACE1 -AS tertiles, ( B ) BACE1 expression across BACE1-AS tertiles. Number of participants in each BACE1-AS tertile: 1st tertile N = 144, 2nd tertile N = 146, 3rd tertile N = 144. p -Values were derived from linear regression analysis. Relative BACE1-AS, BACE1 expression, and plasma Aβ1-40 (pg/mL) were transformed to logarithmic scale prior to analysis. ; Aβ1–40, amyloid β 1–40; BACE1 , β secretase-1; BACE1-AS , β secretase antisense RNA.