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. 2022 Oct 25;2022:4766992. doi: 10.1155/2022/4766992

Figure 6.

Figure 6

m6A-modified inflammatory signaling pathway is expressed in vivo. (a) Dynamic changes of joint swelling in rats. (b) Comparison of toe swelling and arthritis index. ∗p < 0.05, ∗∗p < 0.01 vs NC group (paired t-test). (c) Safranin fast-green staining of joints, X400. (d) Comparison of the expression of cytokines secreted by macrophages.∗p < 0.05, ∗∗∗p < 0.001 (paired t-test). (E) Comparison of the MAPK, PI3K, and AKT inflammatory signaling pathway-related indicators. ∗p < 0.05, ∗∗p < 0.01 (paired t-test). (f) Comparison of the p-MAPK, p-PI3K, p- AKT1, and p-PTEN.∗∗p < 0.01, ∗∗∗p < 0.001 (n = 6, paired t-test). (g) Correlational analysis of signaling pathway-related indicators and joint inflammation.