Figure 2.

Comparison of antibody response between pregnant and nonpregnant persons

The anti-S IgM, IgG, and IgA levels were compared within 7 days before vaccine dosage 1 (t0), 7 days before or after vaccine dosage 2 (t1), and 1–3 weeks post vaccine dosage 2 (t2) between pregnant (red) and nonpregnant persons (blue) using a Mann-Whitney U test. The count is the number of samples captured for the time point. The mean is mean antibody levels. The horizontal dotted line represents the cutoff for positive serology results; ns indicates not significant. The medians (interquartile range) in weeks of samples since dosage 1 are as follows: t0 pregnant, 0.14 (00.29); t0 nonpregnant, 0 (0); t1, pregnant, 3 (0.57); t1 nonpregnant, 3.07 (1.14); t2, pregnant, 5.14 (0.61); t2 nonpregnant, 5.22 (1.17).

Ig, immunoglobulin; t0, blood collected at first time; t1, blood collected at second time; t2, 2 weeks post second dosage.

Prabhu. COVID-19 vaccination in pregnancy. Am J Obstet Gynecol MFM 2023.