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. 2022 Nov 1;12:18418. doi: 10.1038/s41598-022-22107-1

Table 4.

Patients characteristics survival.

Survivors Range Non-survivors Range p
n 90 94
Male 60 (66.7%) 74 (78.7%)
Age [years] 64 (58;70) 25–83 68 (63; 75) 33–92 < 0.05
Body-Mass-Index [kg/m2] 30.45 (26.12; 34.26) 20.81–52.47 27.78 (25.48; 33.14) 18.94–70.31
Time from first symptom to hospital admission [days] 5 (0; 7) 0–50 4.5 (0; 8) 0–23
Time from first symptom to admission to our ICU [days] 10 (5; 14) 0–28 11 (5; 16) 0–35
Time from first symptom to ECMO therapy [days] 16 (13; 22) 4–25 15 (11; 23) 0–31
Direct transfer to our ICU from other hospital 55 (61.1%) 66 (70.2%)
External tracheostomy 6 (6.7%) 8 (8.5%)
External intubation 60 (66.7%) 73 (77.7%)
Invasive mechanical ventilation before admission to our ICU [days] 2 (0; 5) 0–20 3 (0; 7) 0–16
Non-invasive mechanical ventilation before admission to our ICU [days] 2 (1; 3) 1–18 2 (1; 4) 1–22
Charlson ComorbidityIndex 3 (2; 5) 0–11 3 (2; 6) 0–12
Arterial Hypertension 66 (73.3%) 65 (69.1%)
Cardiovascular disease 21 (23.3%) 24 (25.5%)
Neurovascular symptoms 9 (10%) 9 (9.6%)
Coronary artery disease 15 (16.7%) 16 (17.0%)
Thromboembolic events in medical history 4 (4.4%) 7 (7.4%)
Chronic arrhythmias 14 (15.6%) 23 (24.5%)
COPD 8 (8.9%) 5 (5.3%)
Other pulmonary disease 3 (3.3%) 8 (8.5%)
Nicotine abuse 8 (8.9%) 4 (4.3%)
Diabetes mellitus 42 (46.7%) 37 (39.4%)
Previous organ or bone marrow transplantation 4 (4.4%) 5 (5.3%)
Chronic renal failure 12 (13.3%) 16 (17.0%)
Chronic need of renal replacement therapy 1 (1.1%) 7 (7.4%)
Admission with trauma 6 (6.7%) 2 (2.1%)
ACE inhibitors 26 (28.9%) 17 (18.3%)
AT2 receptor blocker 23 (25.6%) 29 (31.2%)
Beta blocker 36 (40.0%) 38 (40.9%)
Antithrombotic drug 24 (26.7%) 25 (26.9%)
DOAC 13 (14.4%) 17 (18.3%)
Corticosteroids 11 (12.2%) 10 (10.8%)
Immunosuppressive Drugs 4 (4.4%) 6 (6.5%)
Nosocomial infection 8 (8.9%) 11 (11.7%)

Data are median (Interquartile range) or n (%).

Significant values are in [bold].

ICU Intensive care unit, ECMO extracorporeal membrane oxygenation, NIV Non-invasive ventilation, COPD Chronic obstructive pulmonary disease, ACE Angiotensin-converting enzyme, AT2 Angiotensin II, DOAC Direct oral anticoagulants.