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. 2022 Nov 1;12:18420. doi: 10.1038/s41598-022-23380-w

Table 2.

Comparison between eyes with and without hyperreflective foci.

HRF (+)
(n = 53)
HRF (−)
(n = 102)
p-value
Age(years) 78.8 ± 7.6 77.3 ± 7.6 0.22
Females 14 (26.4%) 38 (37.3%) 0.18
Presence of pseudodrusen 32 (60.4%) 32 (31.4%) 5.0 × 10−4
Presence of DPED 29 (54.7%) 14 (13.7%) 6.4 × 10−8
Subfoveal choroidal thickness 189 ± 86 226 ± 88 0.013
MNV subtype in the contralateral eye
Type 3 MNV 17 (32.1%) 6 (5.9%) 1.0 × 10−5
Typical neovascular AMD 28 (52.8%) 54 (52.9%) 0.99
PCV 8 (15.1%) 42 (41.2%) 9.8 × 10−4
T allele frequency of ARMS2 A69S 81.1% 69.1% 0.023
G allele frequency of CFH I62Vj 78.3% 76.0% 0.65

HRF, hyperreflective foci; DPED, drusenoid pigment epithelial detachment; MNV, macular neovascularization; RAP, retinal angiomatous proliferation.