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. 2022 Nov 1;12:18392. doi: 10.1038/s41598-022-23168-y

Table 1.

Differences in demographics and clinical characteristics during the acute SARS-CoV-2 infection between patients with persistent symptoms at follow-up and patients recovered.

Study population (n = 75) Patients recovered (n = 29) Patients with persistence of symptoms (PCC children) (n = 46) p
Gender, n (%) Female 37 (49.3%) 13 (44.8%) 24 (52.2%) 0.8
Age (y), median IQR 10.2 (4.9) 10.1 (3) 10.5 (6.7) 0.34
Follow-up (months), median IQR 3.3 (4.6) 3.1 (6) 3.6 (4.4) 0.9
Comorbidities, n (%) 6 (8%) 2 (6.9%) 4 (8.7%) 1
Disease severity, n (%)
Asymptomatic 4 (5.3%) 2 (6.9%) 2 (4.3%) 0.3
Mild 60 (80%) 25 (86.2%) 35 (76.1%)
Moderate/severe 11 (14.7%) 2 (6.9%) 9 (19.6%)
Hospitalization, n (%) 7 (9.3%) 2 (6.9%) 5 (10.9%) 0.7
PICU hospitalization, n (%) 2 (2.7%) 1 (3.4%) 1 (2.2%) 1
Number of symptoms, n (%) median IQR 3 (3) 2 (2) 4 (4) 0.005
Fever, n (%) 52 (69.3%) 17 (58.6%) 35 (76%) 0.1
Days of fever, median IQR 2 (3) 1 (2) 2 (3) 0.002
Rhinitis, n (%) 27 (36%) 12 (41.4%) 15 (32.6%) 0.4
Anosmia, n (%) 22 (29.3%) 5 (17.2%) 17 (37%) 0.06
Dysgeusia, n (%) 18 (24%) 5 (17.2%) 13 (28.3%) 0.2
Cough, n (%) 27 (36%) 8 (27.6%) 19 (41.3%) 0.22
Dyspnea at rest, n (%) 4 (5.3%) 1 (3.4%) 3 (6.5%) 1
Dyspnea under exertion, n (%) 5 (6.7%) 1 (3.4%) 4 (8.7%) 0.6
Asthma, n (%) 2 (2.7%) 0 (0%) 2 (4.3%) 0.5
Chest pain, n (%) 7 (9.3%) 1 (3.4%) 6 (13%) 0.23
Joint pain, n (%) 12 (16%) 1 (3.4%) 11 (23.9%) 0.02
Muscle pain, n (%) 19 (25.3%) 2 (6.9%) 17 (37%) 0.005
Asthenia, n (%) 28 (37.3%) 7 (24.1%) 21 (45.7%) 0.06
Headache, n (%) 31 (41.3%) 10 (34.5%) 21 (45.7%) 0.33
GI disorders, n (%) 10 (13.3%) 1 (3.4%) 9 (19.6%) 0.07
Rash, n (%) 6 (8%) 1 (3.4%) 5 (10.9%) 0.39

ICU intensive care unit, GI gastrointestinal.