Table 3.
Knowledge about RGCS related concepts (n = 384) (Correct answers).
| Knowledge score | ||||
|---|---|---|---|---|
| Mean (SD) | 9.6 (2.74) | |||
| IQR | 8–12 | |||
| Range | 0–14 | |||
| Level of genetic knowledge | N (%) | |||
| Low | 18 (4.7) | |||
| Moderate | 154 (40.1) | |||
| High | 212 (55.2) | |||
| True N (%) | False N (%) | I don’t know N (%) | ||
| 1 | A carrier of an hereditary condition carries a mutation for that condition but does not have the condition himself/herself. | 299 (78.1) | 37 (9.7) | 47 (12.3) |
| 2 | All serious conditions are determined by a genetic predisposition. | 22 (5.7) | 321 (83.3) | 40 (10.4) |
| 3 | All hereditary conditions are expressed during childhood (<18 years). | 12 (3.1) | 313 (81.7) | 58 (15.1) |
| 4 | A carrier screening test examines if you are at risk for developing one or more hereditary conditions. | 135 (35.3) | 174 (45.5) | 73 (19.1) |
| 5 | Genetic carrier screening is only intended for individuals with an increased family risk (families where genetic conditions have already occured). | 90 (23.6) | 221 (58) | 70 (18.4) |
| 6 | You can be a carrier of a hereditary condition without this condition occuring in your own family | 270 (70.3) | 56 (14.6) | 58 (15.1) |
| 7 | A carrier of a hereditary condition will always develop that specific condition and get related health problems. | 9 (2.3) | 339 (88.3) | 36 (9.4) |
| 8 | If you are a carrier of a hereditary condition, all your offspring will also be a carrier of that specific hereditary condition. | 19 (5) | 337 (88) | 27 (7) |
| 9 | If the (future) mother is a carrier of a recessive hereditary condition, all her children will develop this condition. | 7 (1.8) | 288 (75.2) | 88 (23) |
| 10 | If both partners are carriers of a mutation for the same recessive hereditary condition, they a 50% chance each pregnancy to conceive a child with the condition for which they are carriers | 147 (38.3) | 141 (36.7) | 96 (25) |
| 11 | If both partners are carriers of a mutation for a different recessive hereditary condition, they have a 25% chance each pregnancy to conceive a child with one of both condition. | 94 (24.5) | 130 (33.9) | 159 (41.5) |
| 12 | Two healthy individuals without health problems can have a child with an inherited condition. | 315 (82) | 23 (6) | 46 (12) |
| 13 | When a preconceptional genetic carrier screening test does not identify an increased risk, this means with certainty that this couple will have a healthy child. | 17 (4.4) | 308 (80.4) | 58 (15.1) |
| 14 | If both partners are carriers of the same genetic condition, they cannot conceive children naturally without this specific genetic condition. | 24 (6.3) | 251 (65.5) | 108 (28.2) |
Values in italic shown is correct answers.